EPP390 - Associations between suicidal ideation, depression and substance use in university students

EPP390

Associations between suicidal ideation, depression and substance use in university students

E. B. Camargo Júnior 1,*, A. Busatta 1, M. N. D. F. Fernandes 2, L. B. H. Gimenez 3, R. C. D. D. Silva 1, G. G. Silva 1, E. C. D. S. Gherardi-Donato 4

1University of Rio Verde, Rio Verde, 2Federal University of Maranhão, Imperatriz, 3Federal University of Mato Grosso , Sinop, 4Ribeirão Preto School of Nursing – EERP University of São Paulo – USP, Ribeirão Preto, Brazil

 

Introduction: Suicidal ideation is a multifactorial and concerning phenomenon among university students, especially in contexts marked by academic challenges, emotional vulnerability, and substance use.

Objectives: This study aimed to identify the prevalence of suicidal ideation and its association with depression and substance use among Brazilian university students.

Methods: This is a cross-sectional study with a convenience sample composed of students from a multicampus university located in five municipalities in the state of Goiás, Brazil. Participants were undergraduate students aged 18 years or older. Data collection was conducted at the beginning of each academic semester through, self-administered online questionnaire, applied at three time points (Feb/2021, Jul/2021, and Feb/2022). Suicidal ideation was assessed using item 9 of the Patient Health Questionnaire-9 (PHQ-9). Depression was measured using the total PHQ-9 score, with a cutoff point of ≥10. Substance use was assessed using the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST), with participants classified as low or moderate/high risk based on their scores. The study was approved by the Research Ethics Committee (protocol no. 4.434.811).

Results: The sample consisted of 1,271 university students, predominantly women, heterosexuals, single individuals and white. The prevalence of suicidal ideation was 10.14%. The prevalence of depression was 33.4%, with a significant association with suicidal ideation (27.8%; p < 0.001). Bivariate logistic regression indicated a higher likelihood of suicidal ideation among women (OR = 2.61; p < 0.001), sexual minority students (OR = 3.49; p < 0.001), and those with moderate/high-risk alcohol consumption (OR = 2.43; p < 0.001). Depression showed the strongest association, with a 29.3-fold increase in the odds of suicidal ideation (p < 0.001). In the multivariate analysis (Model 2) depression (aOR = 43.34; p < 0.001) and moderate/high-risk tobacco use (aOR = 2.73; p = 0.038) remained significantly associated with suicidal ideation.

Table 1 – Multivariate logistic regression models for factors associated with suicidal ideation among university students.

Variable

Model 1

aOR (95% CI)

p-value

Model 2

aOR (95% CI)

p-value

Depression (present)

24.6 (12.9 – 46.8)

< 0.001

43.34 (5.57 – 337.01)

< 0.001

Tobacco (moderate/high risk)

2.7 (1.43 – 5.24)

0.002

2.73 (1.05 – 7.06)

0.038

Alcohol (moderate/high risk)

2.3 (1.4 – 3.9)

< 0.001

1.06 (0.42 – 2.66)

0.895

Illicit drugs (moderate/high risk)

1.58 (0.89 – 2.80)

0.11

0.98 (0.41 – 2.38)

0.981

Model 1 – adjusted for sex, sexual orientation, and religion.Model 2 – adjusted for sex, sexual orientation, religion, depression, and use of tobacco, alcohol, and illicit drugs.

Conclusions: Suicidal ideation showed high prevalence and was associated with depression and tobacco use. The findings underscore the importance of implementing institutional strategies for mental health screening and care.

 

Disclosure of Interest: None Declared