EPV1094 - Chronic pain intensity predicts long-term depressive disorders in older community-dwellers

EPV1094

Chronic pain intensity predicts long-term depressive disorders in older community-dwellers

I. Rouch 1 2,*, M. Koleck 2, A. Edjolo 3, B. Laurent 4, H. Amieva 2

1neurology, Saint Etienne hospital, Saint Etienne, 2U1219, INSERM, Bordeaux, 3Saint Etienne hospital, Saint Etienne, 4U1028, INSERM, Lyon, France

 

Introduction: Chronic pain (CP) in older adults was associated with depression in numerous cross-sectional studies. However, the longitudinal link between CP characteristics and depressive symptoms in this population remains unsettled. 

 

 

Objectives: We aimed to assess the prospective link between CP intensity and long-term depressive symptoms in a population-based cohort of older participants, considering numerous potential confounders.

Methods: The study sample was gathered from the PAQUID study, a cohort study of older community-dwellers above 65. Information regarding CP characteristics was collected at the 3-year follow-up visit. The sample included the 713 participants who fulfilled this CP questionnaire. Three groups of CP were distinguished: no, mild and intense CP. Depressive symptoms were assessed with the Center for Epidemiologic Studies Depression scale (CES-D) scale every 2 to 3 years during 12 years. The association between CP and the 12-year CES-D course was investigated using a multivariate latent process mixed model for curvilinear data.

Results: Compared with the participants without CP, those with moderate and intense CP had significantly higher CES-D levels at baseline with a dose-response relationship as a function of pain intensity (β =0.391, p=0.0224, and 0.696, p <. 0001, respectively). However, the time course was comparable in the three groups (β =-0.003, p=0.8406, and 0.001, p = 0.9617, for mild and intense CP respectively).

 

Conclusions: CP intensity is associated with higher levels of depressive symptoms persisting throughout the long period of follow-up. This finding reinforces the importance of early treatment of CP in older adults, to prevent its sustainable psychological consequences.

 

Disclosure of Interest: None Declared